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 About Glaucoma | Glossary

Glossary

  • allergic conjunctivitis: the eye's reaction to allergy-causing substances like pollen and dander. Allergic conjunctivitis may include symptoms like eye redness, tearing, and itching.3
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  • aqueous humor: a transparent fluid occupying the front and rear chambers of the eye, nourishing the lens and cornea.4
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  • chronic disease: a condition that persists for a long time and generally cannot be prevented by vaccines or cured by medication.4
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  • contraindication: a condition which makes a particular treatment or procedure inadvisable.4
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  • drainage channel: also known as the drainage angle, where fluid flows from the eye; if these channels are blocked, high eye pressure can result.4
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  • glaucoma: a disease of the eye marked by increased pressure within the eyeball that can result in damage to the optic nerve and gradual loss of vision.4
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  • intraocular pressure (IOP): the pressure within the eyeball created by the continual renewal of fluids within the eye.4
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  • laser surgery (for glaucoma): laser surgery that involves either laser treatment or making a cut in the eye to reduce the intraocular pressure (IOP). The type of surgery your doctor recommends will depend on the type and severity of your glaucoma and the general health of your eye. Surgery can help lower pressure when medication is not sufficient; however, it cannot reverse vision loss.5
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  • nearsighted: able to see near things more clearly than distant ones.4
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  • ocular hypertension: an increase in the pressure in your eyes that is above normal, with no detectable changes in vision or damage to your eyes. You can have elevated eye pressure without having glaucoma, an eye disease that causes damage to the optic nerve and vision loss.6
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  • open-angle glaucoma: occurs when the aqueous (fluid) in the eye cannot drain through a filtration system called the trabecular meshwork, causing pressure in the eye to increase, damaging the optic nerve and impairing vision; open-angle glaucoma is the most common form of glaucoma.4
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  • optic nerve: a bundle of more than 1 million nerve fibers that connects the retina to the brain.2
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  • surgery (for glaucoma): surgery makes a new opening for the fluid to leave the eye.5
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  • visual acuity: how well you see at various distances.2
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  • visual field: the entire area that can be seen at a given instant without moving the eyes.4
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Indication: COMBIGAN® (brimonidine tartrate/timolol maleate ophthalmic solution) 0.2%/0.5% is approved for reducing elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP. COMBIGAN® lowers IOP slightly less than taking both brimonidine tartrate three times a day and timolol maleate two times a day.

IMPORTANT SAFETY INFORMATION
Contraindications: COMBIGAN® ophthalmic solution should not be used by patients who have or ever had a reactive airway disease including bronchial asthma, chronic bronchitis, emphysema, slow heartbeat, impaired conduction of the heart, heart failure, or impaired pumping of the heart. COMBIGAN® should not be used in patients aged 2 years and younger, or by patients with hypersensitivity to any ingredient in this product.

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