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  1. American Health Assistance Foundation. Glaucoma statistics. American Health Assistance Foundation website. http://www.ahaf.org/glaucoma/about/understanding/facts.html. Accessed September 14, 2014.
  2. National Eye Institute. Facts about glaucoma. National Eye Institute website. http://www.nei.nih.gov/health/glaucoma/glaucoma_facts.asp.
    Accessed September 14, 2014.
  3. MedlinePlus®. Medical encyclopedia. US National Library of Medicine and the National Institutes of Health website. http://www.nlm.nih.gov/medlineplus/encyclopedia.html.
    Accessed September 14, 2014.
  4. MedTerms®. MedicineNet.com website. http://www.medterms.com/script/main/hp.asp.
    Accessed September 14, 2014.
  5. Glaucoma Research Foundation. Glaucoma surgery. Glaucoma Research Foundation website. http://www.glaucoma.org/treatment/surgery-overview.php. Accessed September 14, 2014.
  6. American Optometric Association. Ocular hypertension. American Optometric Association website. http://www.aoa.org/patients-and-public/eye-and-vision-problems/glossary-of-eye-and-vision-conditions/ocular-hypertension?sso=y. Accessed September 14, 2014.
  7. COMBIGAN® Prescribing Information.

Indication: COMBIGAN® (brimonidine tartrate/timolol maleate ophthalmic solution) 0.2%/0.5% is approved for reducing elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP. COMBIGAN® lowers IOP slightly less than taking both brimonidine tartrate three times a day and timolol maleate two times a day.

Contraindications: COMBIGAN® ophthalmic solution should not be used by patients who have or ever had a reactive airway disease including bronchial asthma, chronic bronchitis, emphysema, slow heartbeat, impaired conduction of the heart, heart failure, or impaired pumping of the heart. COMBIGAN® should not be used in patients aged 2 years and younger, or by patients with hypersensitivity to any ingredient in this product.

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